Gluten-Free Diet May Ease Schizophrenia Symptoms

Gluten-Free Diet May Ease Schizophrenia Symptoms (medscape.com)

[Medscape, 4/15/19]  A gluten-free diet may reduce symptoms in a particular subset of patients with schizophrenia, early research suggests.

In a small pilot study, investigators found individuals with schizophrenia who have elevated serum antibodies to gluten, specifically antigliadin antibodies (AGA IgG) and who were put on a gluten-free-diet for 5 weeks showed greater improvement in negative symptoms compared with their counterparts who ate a diet containing gluten.

“With a gluten-free diet, we do have the potential to improve psychiatric symptoms, particularly negative symptoms, which is a symptom domain with a high unmet clinical need,” said lead investigator Deanna L. Kelly, PharmD, professor of psychiatry, University of Maryland School of Medicine, Baltimore.

“We don’t have anything for negative symptoms, so this could be a treatment for people if they have these antigliadin antibodies,” Kelly said.

The findings were presented here at the first annual Congress of the Schizophrenia International Research Society (SIRS) 2019.

30% Gluten Intolerant
Elevated AGA IgG may be present in about 30% of all patients with schizophrenia. The antigliadin antibody is not related to the antibodies seen in celiac disease, which affects roughly 1% of the overall population……..


Read the Full Article at: Medscape

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