Male Contraceptive Gel to Be Evaluated in Clinical Trial
[MPR, 11/29/18] The safety and efficacy of a male contraceptive gel, developed by the Population Council and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), will be evaluated in a clinical trial to determine its ability to prevent pregnancy.
The year-long Phase 2b trial, funded by the National Institutes of Health, will enroll approximately 420 couples that are seeking pregnancy prevention across 3 US sites (Los Angeles, Seattle, and Kansas City). Future trial sites will include Chile, England, Italy, Kenya, Scotland, and Sweden.
The NES/T gel is composed of Nestorone (segesterone acetate), a progestin hormone used for female contraception, and testosterone. The transparent gel is intended to be absorbed through the skin on the upper arms and shoulders and works by reducing sperm production while maintaining normal sex drive. The trial will also examine the acceptability of the daily gel as a contraceptive method among the study couples……..
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