Preeclampsia Linked to Later Stroke Risk, Aspirin May Help

[Medscape, 1/3/19]  Having preeclampsia or other forms of hypertension during pregnancy puts women at increased risk of stroke, which may be mitigated by long-term use of aspirin, a new study suggests.

“Women at high risk of developing preeclampsia are given aspirin during pregnancy and we know this reduces their risk of developing the condition, but the aspirin is usually stopped after delivery. The question remains as to whether aspirin should be continued in these women,” lead author Eliza C. Miller, MD, Columbia University Mailman School of Public Health, New York City, commented to Medscape Medical News.

“This study doesn’t answer that question, but we show some interesting and thought-provoking findings,” she said. “We saw a trend towards benefit of aspirin in women who had experienced hypertension in pregnancy in this study but the effect was not significant in the whole group. However, women in their 40s and 50s saw the most benefit and the effect was significant in this age group. It is possible that the effect gets diluted as women age.”

In the younger group (under 60 years), women not on aspirin but with a history of hypertension in pregnancy had a 50% increased risk of stroke compared with women who did not have a history of hypertension during pregnancy, even after adjusting for many other risk factors, the study showed. However, women with a history of hypertension during pregnancy but who took aspirin did not show an increased stroke risk. “It therefore seems like aspirin has a beneficial effect in this group who are at increased risk of stroke in middle age,” Miller commented……………….

Read the Full Article at: Medscape

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